Ontology highlight
ABSTRACT:
SUBMITTER: Vigouroux A
PROVIDER: S-EPMC7002073 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
eLife 20200106
Cell shape and cell-envelope integrity of bacteria are determined by the peptidoglycan cell wall. In rod-shaped <i>Escherichia coli</i>, two conserved sets of machinery are essential for cell-wall insertion in the cylindrical part of the cell: the Rod complex and the class-A penicillin-binding proteins (aPBPs). While the Rod complex governs rod-like cell shape, aPBP function is less well understood. aPBPs were previously hypothesized to either work in concert with the Rod complex or to independe ...[more]