Quantifying the biochemical state of knee cartilage in response to running using T1rho magnetic resonance imaging.

ABSTRACT: Roughly 20% of Americans run annually, yet how this exercise influences knee cartilage health is poorly understood. To address this question, quantitative magnetic resonance imaging (MRI) can be used to infer the biochemical state of cartilage. Specifically, T1rho relaxation times are inversely related to the proteoglycan concentration in cartilage. In this study, T1rho MRI was performed on the dominant knee of eight asymptomatic, male runners before, immediately after, and 24?hours after running 3 and 10 miles. Overall, (mean?±?SEM) patellar, tibial, and femoral cartilage T1rho relaxation times significantly decreased immediately after running 3 (65?±?3?ms to 62?±?3?ms; p?=?0.04) and 10 (69?±?4?ms to 62?±?3?ms; p?

SUBMITTER: Heckelman LN 

PROVIDER: S-EPMC7002650 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature