Unknown

Dataset Information

0

Association between retinal microvasculature and optic disc alterations in high myopia.


ABSTRACT: PURPOSE:This study aimed to explore the characteristics of retinal perfusion and its associations with high myopia. METHODS:A total of 760 participants were included. Peripapillary radial peripapillary capillary perfusion, foveal avascular zone, and parafoveal perfusion were measured using optical coherence tomography angiography (OCTA). Tilted disc ratio and parapapillary atrophy were determined using swept-source optical coherence tomography. RESULTS:A total of 760 young healthy participants with myopic eyes were included in the analysis. The mean axial length and titled disc ratio were 26.43?±?1.14 and 0.76?±?0.08?mm in the high-myopia group and 24.79?±?0.75 and 0.80?±?0.09?mm in the control group, respectively. The high-myopia group exhibited significantly larger parapapillary atrophy, lower tilted disc ratio, lower radial peripapillary capillary vessel density, larger area of foveal avascular zone, and lower deep parafoveal vessel density. In the multivariate analysis, titled disc ratio significantly correlated with radial peripapillary capillary vessel density (P?=?0.0134), larger foveal avascular zone (P?=?0.0062), and lower deep parafoveal vessel density (P?

SUBMITTER: He J 

PROVIDER: S-EPMC7002767 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

altmetric image

Publications

Association between retinal microvasculature and optic disc alterations in high myopia.

He Jiangnan J   Chen Qiuying Q   Yin Yao Y   Zhou Hongfeng H   Fan Ying Y   Zhu Jianfeng J   Zou Haidong H   Xu Xun X  

Eye (London, England) 20190424 9


<h4>Purpose</h4>This study aimed to explore the characteristics of retinal perfusion and its associations with high myopia.<h4>Methods</h4>A total of 760 participants were included. Peripapillary radial peripapillary capillary perfusion, foveal avascular zone, and parafoveal perfusion were measured using optical coherence tomography angiography (OCTA). Tilted disc ratio and parapapillary atrophy were determined using swept-source optical coherence tomography.<h4>Results</h4>A total of 760 young  ...[more]

Similar Datasets

| S-EPMC8648062 | biostudies-literature
| S-EPMC5536188 | biostudies-literature
| S-EPMC6375117 | biostudies-literature
| S-EPMC8170317 | biostudies-literature
| S-EPMC4274005 | biostudies-literature
| S-EPMC8320981 | biostudies-literature
| S-EPMC8065167 | biostudies-literature
| S-EPMC11018332 | biostudies-literature
| S-EPMC5527847 | biostudies-other
| S-EPMC6080778 | biostudies-literature