Psychotropic Polypharmacy in Adults 55 Years or Older: A Risk for Impaired Global Cognition, Executive Function, and Mobility.

ABSTRACT:

Objectives

With their broad spectrum of action, psychotropic drugs are among the most common medications prescribed to the elderly. Consequently, the number of older adults taking multiple psychotropic drugs has more than doubled over the last decade. To improve knowledge about the deleterious effects of psychotropic polypharmacy, we investigated whether there is a threshold number of psychotropic molecules that could lead to impairment of global cognition, executive function, or mobility. Furthermore, relationships between the number of psychotropic molecules and cognitive and mobility impairment were examined.

Design

Cross-sectional study.

Setting

University Hospital of Caen (France) and advertisements in medical offices.

Participants

Community-dwelling older

SUBMITTER: Loggia G 

PROVIDER: S-EPMC7002919 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature