Protective effect of vitamin C on chronic carbamazepine-induced reproductive toxicity in male wistar rats.
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ABSTRACT:
SUBMITTER: Akorede GJ
PROVIDER: S-EPMC7005556 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Protective effect of vitamin C on chronic carbamazepine-induced reproductive toxicity in male wistar rats.
Toxicology reports 20200127
The aim of this study was to evaluate the protective effect of vitamin C on chronic carbamazepine-induced reproductive toxicity in male Wistar rats. Four groups of 10 rats were respectively exposed to distilled water (2 ml/kg), vitamin C (100 mg/kg), carbamazepine (20 mg/kg) and vitamin C followed by CBZ, after 30 min.. The regimens were given by gavage once daily for 15 weeks. The pituitary glands and testicular tissues were assayed for oxidative stress parameters, sperm characteristics, relati ...[more]
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