Ontology highlight
ABSTRACT:
SUBMITTER: Kim MG
PROVIDER: S-EPMC7005727 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Kim Myung-Gyu MG Lim Kijoon K Lee Yoo Jin YJ Yang Jihyun J Oh Se Won SW Cho Won Yong WY Jo Sang-Kyung SK
Scientific reports 20200207 1
Although macrophages are important players in the injury/repair processes in animal models of acute kidney injury (AKI), their roles in human AKI remains uncertain owing to a paucity of human biopsy studies. We investigated the role of macrophages in 72 cases of biopsy-proven acute tubular necrosis (ATN) and six cases of healthy kidney. Macrophages were identified by CD68 and CD163 immunohistochemistry and analyzed for their effect on renal outcomes. CD163+ M2 macrophages outnumbered CD68+ cells ...[more]