Ontology highlight
ABSTRACT:
SUBMITTER: Hutchinson JA
PROVIDER: S-EPMC7005981 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
The journal of physical chemistry. B 20190114 3
We investigate the impact of lipidation on the self-assembly of two peptide fragments from the gastrointestinal peptide hormone PYY<sub>3-36</sub>. The lipopeptides C<sub>16</sub>IKPEAP and C<sub>16</sub>IKPEAPGE contain the first 6 and 8 amino acid residues, respectively, from the PYY<sub>3-36</sub> peptide sequence, with a palmitoyl C<sub>16</sub> tail attached at the N-terminus. These lipopeptides form spherical micelles in aqueous solution, above a critical micelle concentration (cmc), which ...[more]