Ontology highlight
ABSTRACT:
SUBMITTER: Muriel B
PROVIDER: S-EPMC7006509 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Chemical science 20191008 46
We report the convergent synthesis of bicyclo[3.1.0]hexanes possessing an all-carbon quaternary center <i>via</i> a (3 + 2) annulation of cyclopropenes with cyclopropylanilines. Using an organic or an iridium photoredox catalyst and blue LED irradiation, good yields were obtained for a broad range of cyclopropene and cyclopropylaniline derivatives. The reaction was highly diastereoselective when using difluorocyclopropenes together with a removable substituent on the cyclopropylaniline, giving a ...[more]