Ontology highlight
ABSTRACT:
SUBMITTER: Eldrid C
PROVIDER: S-EPMC7006968 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Eldrid Charles C Ujma Jakub J Kalfas Symeon S Tomczyk Nick N Giles Kevin K Morris Mike M Thalassinos Konstantinos K
Analytical chemistry 20190605 12
Ion mobility mass spectrometry (IM-MS) allows separation of native protein ions into "conformational families". Increasing the IM resolving power should allow finer structural information to be obtained and can be achieved by increasing the length of the IM separator. This, however, increases the time that protein ions spend in the gas phase and previous experiments have shown that the initial conformations of small proteins can be lost within tens of milliseconds. Here, we report on investigati ...[more]