Ontology highlight
ABSTRACT:
SUBMITTER: Sinha S
PROVIDER: S-EPMC7007354 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Sinha Sonali S Dwivedi Nidhi N Tao Shixin S Jamadar Abeda A Kakade Vijayakumar R VR Neil Maura O' MO Weiss Robert H RH Enders Jonathan J Calvet James P JP Thomas Sufi M SM Rao Reena R
Oncogene 20191015 6
Arginine vasopressin (AVP) and its type-2 receptor (V2R) play an essential role in the regulation of salt and water homeostasis by the kidneys. V2R activation also stimulates proliferation of renal cell carcinoma (RCC) cell lines in vitro. The current studies investigated V2R expression and activity in human RCC tumors, and its role in RCC tumor growth. Examination of the cancer genome atlas (TCGA) database, and analysis of human RCC tumor tissue microarrays, cDNA arrays and tumor biopsy samples ...[more]