Ontology highlight
ABSTRACT:
SUBMITTER: Baksh KA
PROVIDER: S-EPMC7008368 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Baksh Karina A KA Zamble Deborah B DB
The Journal of biological chemistry 20191219 6
Many transition metals are essential trace nutrients for living organisms, but they are also cytotoxic in high concentrations. Bacteria maintain the delicate balance between metal starvation and toxicity through a complex network of metal homeostasis pathways. These systems are coordinated by the activities of metal-responsive transcription factors-also known as metal-sensor proteins or metalloregulators-that are tuned to sense the bioavailability of specific metals in the cell in order to regul ...[more]