Ontology highlight
ABSTRACT:
SUBMITTER: Khalil M
PROVIDER: S-EPMC7010701 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Khalil Michael M Pirpamer Lukas L Hofer Edith E Voortman Margarete M MM Barro Christian C Leppert David D Benkert Pascal P Ropele Stefan S Enzinger Christian C Fazekas Franz F Schmidt Reinhold R Kuhle Jens J
Nature communications 20200210 1
Neurofilament light (NfL) protein is a marker of neuro-axonal damage and can be measured not only in cerebrospinal fluid but also in serum, which allows for repeated assessments. There is still limited knowledge regarding the association of serum NfL (sNfL) with age and subclinical morphologic brain changes and their dynamics in the normal population. We measured sNfL by a single molecule array (Simoa) assay in 335 individuals participating in a population-based cohort study and after a mean fol ...[more]