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Practical Synthesis of Ethynyl(phenyl)-?3-Iodane Using Calcium Carbide as an Ethynyl Group Source.

ABSTRACT: Stannylation of calcium carbide followed by Sn-hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-?3-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions.

SUBMITTER: Hashishin T

PROVIDER: S-EPMC7010717 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Practical Synthesis of Ethynyl(phenyl)-λ<sup>3</sup>-Iodane Using Calcium Carbide as an Ethynyl Group Source.

Hashishin Takahiro T Osawa Taisei T Miyamoto Kazunori K Uchiyama Masanobu M

Frontiers in chemistry 20200204

Stannylation of calcium carbide followed by Sn-hypervalent iodine(III) exchange reaction cleanly afforded the electrophilic ethynylating agent ethynyl(phenyl)-λ<sup>3</sup>-iodane in high yield. This two-step method uses very inexpensive materials and is readily operable without any special precautions. ...[more]

PMID: 32117863

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