Ontology highlight
ABSTRACT:
SUBMITTER: Zhao D
PROVIDER: S-EPMC7011352 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Cancer cell international 20200210
<h4>Background</h4>This study is to investigate the effects of zoledronic acid (ZA) on TSC2-null cell proliferation and on the tumor progression and recurrence in mouse models of lymphangioleiomyomatosis (LAM).<h4>Methods</h4>Subcutaneous mouse models and LAM mouse models were established. Immunohistochemistry and immunofluorescence were performed to detect the protein expression levels. TUNEL assay was conducted to detect cell apoptosis. Immunoprecipitation was carried out to determine the inte ...[more]