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Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.


ABSTRACT: We assessed whether blood lipid metabolites and their changes associate with various cardiometabolic, endocrine, bone- and energy-related comorbidities of Relative Energy Deficiency in Sport (RED-S) in female elite endurance athletes. Thirty-eight Scandinavian female elite athletes underwent a day-long exercise test. Five blood samples were obtained during the day - at fasting state and before and after two standardized exercise tests. Clinical biomarkers were assessed at fasting state, while untargeted lipidomics was undertaken using all blood samples. Linear and logistic regression was used to assess associations between lipidomic features and clinical biomarkers. Overrepresentations of findings with P?

SUBMITTER: Varga TV 

PROVIDER: S-EPMC7012926 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Lipidomic profiles, lipid trajectories and clinical biomarkers in female elite endurance athletes.

Varga Tibor V TV   Ali Ashfaq A   Herrera Jose A R JAR   Ahonen Linda L LL   Mattila Ismo M IM   Al-Sari Naba H NH   Legido-Quigley Cristina C   Skouby Sven S   Brunak Søren S   Tornberg Åsa B ÅB  

Scientific reports 20200211 1


We assessed whether blood lipid metabolites and their changes associate with various cardiometabolic, endocrine, bone- and energy-related comorbidities of Relative Energy Deficiency in Sport (RED-S) in female elite endurance athletes. Thirty-eight Scandinavian female elite athletes underwent a day-long exercise test. Five blood samples were obtained during the day - at fasting state and before and after two standardized exercise tests. Clinical biomarkers were assessed at fasting state, while un  ...[more]

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