Ontology highlight
ABSTRACT:
SUBMITTER: Bordewijk EM
PROVIDER: S-EPMC7013239 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Bordewijk Esmée M EM Ng Ka Ying Bonnie KYB Rakic Lidija L Mol Ben Willem J BWJ Brown Julie J Crawford Tineke J TJ van Wely Madelon M
The Cochrane database of systematic reviews 20200211
<h4>Background</h4>Polycystic ovary syndrome (PCOS) is a common condition affecting 8% to 13% of reproductive-aged women. In the past clomiphene citrate (CC) used to be the first-line treatment in women with PCOS. Ovulation induction with letrozole should be the first-line treatment according to new guidelines, but the use of letrozole is off-label. Consequently, CC is still commonly used. Approximately 20% of women on CC do not ovulate. Women who are CC-resistant can be treated with gonadotroph ...[more]