Ontology highlight
ABSTRACT:
SUBMITTER: Hadjicharalambous MR
PROVIDER: S-EPMC7013390 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Hadjicharalambous Marina R MR Lindsay Mark A MA
International journal of molecular sciences 20200114 2
Idiopathic pulmonary fibrosis (IPF) is a progressive chronic disease characterized by excessing scarring of the lungs leading to irreversible decline in lung function. The aetiology and pathogenesis of the disease are still unclear, although lung fibroblast and epithelial cell activation, as well as the secretion of fibrotic and inflammatory mediators, have been strongly associated with the development and progression of IPF. Significantly, long non-coding RNAs (lncRNAs) are emerging as modulato ...[more]