Ontology highlight
ABSTRACT:
SUBMITTER: Germain K
PROVIDER: S-EPMC7013971 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200116 2
The removal of damaged or superfluous organelles from the cytosol by selective autophagy is required to maintain organelle function, quality control and overall cellular homeostasis. Precisely how substrate selectivity is achieved, and how individual substrates are degraded during selective autophagy in response to both extracellular and intracellular cues is not well understood. The aim of this review is to highlight pexophagy, the autophagic degradation of peroxisomes, as a model for selective ...[more]