Ontology highlight
ABSTRACT:
SUBMITTER: Evrova O
PROVIDER: S-EPMC7014238 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Evrova Olivera O Kellenberger Damian D Calcagni Maurizio M Vogel Viola V Buschmann Johanna J
International journal of molecular sciences 20200110 2
Cell-based tendon therapies with tenocytes as a cell source need effective tenocyte in vitro expansion before application for tendinopathies and tendon injuries. Supplementation of tenocyte culture with biomolecules that can boost proliferation and matrix synthesis is one viable option for supporting cell expansion. In this in vitro study, the impacts of ascorbic acid or PDGF-BB supplementation on rabbit Achilles tenocyte culture were studied. Namely, cell proliferation, changes in gene expressi ...[more]