Dataset Information

Seroprevalence of hepatitis E virus among blood donors on Corsica, France, 2017.

ABSTRACT: BackgroundHepatitis E virus (HEV) is an emerging zoonotic pathogen and an important cause of acute viral hepatitis in European countries. Corsica Island has been previously identified as a hyperendemic area for HEV.AimOur aim was to characterise the prevalence and titres of IgG antibodies to HEV among blood donors on Corsica and establish a model of the annual force of infection.MethodsBetween September 2017 and January 2018, 2,705 blood donations were tested for anti-HEV IgG using the Wantai HEV IgG enzyme immunoassay.ResultsThe overall seroprevalence was 56.1%. In multivariate analysis, seroprevalence was higher in men than in women (60.0% vs 52.2%; p?

SUBMITTER: Capai L

PROVIDER: S-EPMC7014670 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Seroprevalence of hepatitis E virus among blood donors on Corsica, France, 2017.

Capai Lisandru L Hozé Nathanaël N Chiaroni Jacques J Gross Sylvie S Djoudi Rachid R Charrel Rémi R Izopet Jacques J Bosseur Frédéric F Priet Stéphane S Cauchemez Simon S de Lamballerie Xavier X Falchi Alessandra A Gallian Pierre P

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20200201 5

BackgroundHepatitis E virus (HEV) is an emerging zoonotic pathogen and an important cause of acute viral hepatitis in European countries. Corsica Island has been previously identified as a hyperendemic area for HEV.AimOur aim was to characterise the prevalence and titres of IgG antibodies to HEV among blood donors on Corsica and establish a model of the annual force of infection.MethodsBetween September 2017 and January 2018, 2,705 blood donations were tested for anti-HEV IgG using the Wantai HE ...[more]

PMID: 32046820

Similar Datasets

Project description:BACKGROUND:High-risk population of blood donation increases the prevalence of transmit blood-borne diseases and harm the blood safety. Syphilis accounts for approximately 10% of commonly sexually transmitted diseases. The risk factors for blood donors infected with syphilis are also risk factors for other blood borne diseases. The objective of the study is to investigate the seroprevalence and risk factors on syphilis among blood donors, and analyze the donation status of high-risk population. METHODS:A retrospective study was conducted in Chengdu Blood Center during 2005 and 2017. Serological test results of volunteer blood donors were collected. Conditional logistic regression models were performed to investigate syphilis-related risk factors and population attributable risk (PAR) was performed to predict the tendencies of high-risk populations' on risky behaviors. RESULTS:The serological epidemic for syphilis among blood donors in Chengdu showed an upward trend from 2005 to 2017.TP positive blood donors were more likely to have multiple sexual partners and commercial sex (50.6% vs.22.6, 11.1% vs.4.6%). Multiple condition logistic regression model denoted the following risk factors for increasing rates of syphilis infections: multiple sexual partners (OR = 7.1, 95% CI:1.72-6.58), razor reuse (OR = 1.7;, 95% CI:1.01-2.01); ear piercing (OR = 2.7, 95% CI:1.48-3.37); tattoo (OR = 3.3, 95% CI:1.17-6.78); condom occasionally (OR = 2.8, 95% CI:0.68-1.66). The PAR for each of the risk factors were 0.225, 0.144, 0.147, 0.018, 0.129, 0.018, respectively. CONCLUSION:Health consultation and screening of high-risk groups before blood donation need to be further improved. Blood donor recruitment should emphasize on excluding the high-risk donors and recruiting more low-risk blood donors. In addition, this study also shows that sharing cosmetic surgical instrument has been proven to transmit blood-borne diseases. Therefore, the syphilis in blood circulation should not be ignored.

Dataset Information

Seroprevalence of hepatitis E virus among blood donors on Corsica, France, 2017.

Publications

Seroprevalence of hepatitis E virus among blood donors on Corsica, France, 2017.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets