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Blastocyst hatching site is regularly distributed and does not influence foetal development in mice.


ABSTRACT: Hatching out from the zona pellucida (ZP) is a crucial step for blastocyst implantation and development. However, it is still unknown whether the location of the hatching site relative to the inner cell mass (ICM) affects embryo implantation and foetal development. Here, we classified hatching blastocysts into three categories, 0°???????30°, 30°?

SUBMITTER: Liu SJ 

PROVIDER: S-EPMC7015891 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Blastocyst hatching site is regularly distributed and does not influence foetal development in mice.

Liu Shu-Jun SJ   Sun Jia-Bo JB   Hao Xin X   Han Zhe Z   Wen Xin X   Wang Xing-Yue XY   Zhou Cheng-Jie CJ   Liang Cheng-Guang CG  

Scientific reports 20200212 1


Hatching out from the zona pellucida (ZP) is a crucial step for blastocyst implantation and development. However, it is still unknown whether the location of the hatching site relative to the inner cell mass (ICM) affects embryo implantation and foetal development. Here, we classified hatching blastocysts into three categories, 0° ≤ θ ≤ 30°, 30° < θ ≤ 60°, and 60° < θ ≤ 90°, in which θ is determined based on the relative position of the hatching site to the arc midpoint of the ICM. Non-surgical  ...[more]

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