MorbiNet: multimorbidity networks in adult general population. Analysis of type 2 diabetes mellitus comorbidity.

ABSTRACT: Multimorbidity has great impact on health care. We constructed multimorbidity networks in the general population, extracted subnets focused on common chronic conditions and analysed type 2 diabetes mellitus (T2DM) comorbidity network. We used electronic records from 3,135,948 adult people in Catalonia, Spain (539,909 with T2DM), with at least 2 coexistent chronic conditions within the study period (2006-2017). We constructed networks from odds-ratio estimates adjusted by age and sex and considered connections with OR > 1.2 and p-value < 1e-5. Directed networks and trajectories were derived from temporal associations. Interactive networks are freely available in a website with the option to customize characteristics and subnets. The more connected conditions in T2DM undirected network were:

SUBMITTER: Aguado A 

PROVIDER: S-EPMC7016191 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature