Angioregulatory microRNAs in Colorectal Cancer.
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ABSTRACT:
SUBMITTER: Soheilifar MH
PROVIDER: S-EPMC7016698 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Angioregulatory microRNAs in Colorectal Cancer.
Soheilifar Mohammad Hasan MH Grusch Michael M Neghab Hoda Keshmiri HK Amini Razieh R Maadi Hamid H Saidijam Massoud M Wang Zhixiang Z
Cancers 20191226 1
Colorectal cancer (CRC) is one of the leading causes of cancer mortality. Angiogenesis is a rate-determining step in CRC development and metastasis. The balance of angiogenic and antiangiogenic factors is crucial in this process. Angiogenesis-related genes can be regulated post-transcriptionally by microRNAs (miRNAs) and some miRNAs have been shown to shuttle between tumor cells and the tumor microenvironment (TME). MiRNAs have context-dependent actions and can promote or suppress angiogenesis d ...[more]
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