Ontology highlight
ABSTRACT:
SUBMITTER: Hornos Carneiro MF
PROVIDER: S-EPMC7017011 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Hornos Carneiro Maria Fernanda MF Shin Nara N Karthikraj Rajendiran R Barbosa Fernando F Kannan Kurunthachalam K Colaiácovo Monica P MP
Genetics 20191218 2
Endocrine-disrupting chemicals are ubiquitously present in our environment, but the mechanisms by which they adversely affect human reproductive health and strategies to circumvent their effects remain largely unknown. Here, we show in <i>Caenorhabditis elegans</i> that supplementation with the antioxidant Coenzyme Q10 (CoQ10) rescues the reprotoxicity induced by the widely used plasticizer and endocrine disruptor bisphenol A (BPA), in part by neutralizing DNA damage resulting from oxidative str ...[more]