Ontology highlight
ABSTRACT:
SUBMITTER: Ong MS
PROVIDER: S-EPMC7017214 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Ong Mei Shan MS Deng Shuo S Halim Clarissa Esmeralda CE Cai Wanpei W Tan Tuan Zea TZ Huang Ruby Yun-Ju RY Sethi Gautam G Hooi Shing Chuan SC Kumar Alan Prem AP Yap Celestial T CT
Cancers 20200118 1
Cytoskeletal proteins, which consist of different sub-families of proteins including microtubules, actin and intermediate filaments, are essential for survival and cellular processes in both normal as well as cancer cells. However, in cancer cells, these mechanisms can be altered to promote tumour development and progression, whereby the functions of cytoskeletal proteins are co-opted to facilitate increased migrative and invasive capabilities, proliferation, as well as resistance to cellular an ...[more]