Ontology highlight
ABSTRACT:
SUBMITTER: Degirmenci U
PROVIDER: S-EPMC7017232 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Degirmenci Ufuk U Wang Mei M Hu Jiancheng J
Cells 20200113 1
The RAS/RAF/MEK/ERK (MAPK) signaling cascade is essential for cell inter- and intra-cellular communication, which regulates fundamental cell functions such as growth, survival, and differentiation. The MAPK pathway also integrates signals from complex intracellular networks in performing cellular functions. Despite the initial discovery of the core elements of the MAPK pathways nearly four decades ago, additional findings continue to make a thorough understanding of the molecular mechanisms invo ...[more]