Ontology highlight
ABSTRACT:
SUBMITTER: Maya-Ramos L
PROVIDER: S-EPMC7017582 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20200101 6474
Bilateral symmetry is the predominant body plan in the animal kingdom. Cells on the left and right sides remain compartmentalized on their ipsilateral side throughout life, but with occasional variation, as evidenced by gynandromorphs and human disorders. How this evolutionarily conserved body plan is programmed remains a fundamental yet unanswered question. Here, we show that germ-layer patterning in avian gastrulation is ipsilateral despite cells undergoing highly invasive mesenchymal transfor ...[more]