Ontology highlight
ABSTRACT:
SUBMITTER: Huang Y
PROVIDER: S-EPMC7017730 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Huang Yake Y Huang Jiani J Huang Yan Y Gan Lei L Long Ling L Pu Aimin A Xie Rongkai R
American journal of cancer research 20200101 1
Epithelial ovarian cancer (EOC) is the most common cause of gynecological cancer death. Recent studies have reported that iron overload could accelerate cancer progression. TFRC is an important participant in intracellular iron transport, and we noticed that it was abnormally overexpressed in EOC; however, its specific role in EOC remained unclear. Therefore, our study aimed to reveal the clinical significance and biological function of TFRC in human EOC. First, we detected dramatically increase ...[more]