Ontology highlight
ABSTRACT:
SUBMITTER: Wang H
PROVIDER: S-EPMC7018668 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in cell and developmental biology 20200207
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, leading to a large global cancer burden. Hepatocyte growth factor (HGF) and its high-affinity receptor, mesenchymal epithelial transition factor (c-Met), are closely related to the onset, progression, and metastasis of multiple tumors. The HGF/c-Met axis is involved in cell proliferation, movement, differentiation, invasion, angiogenesis, and apoptosis by activating multiple downstream signaling pathways. In this re ...[more]