Ontology highlight
ABSTRACT:
SUBMITTER: Shinde A
PROVIDER: S-EPMC7018754 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Oncogenesis 20200213 2
The ability of breast cancer cells to interconvert between epithelial and mesenchymal states contributes to their metastatic potential. As opposed to cell autonomous effects, the impact of epithelial-mesenchymal plasticity (EMP) on primary and metastatic tumor microenvironments remains poorly characterized. Herein we utilize global gene expression analyses to characterize a metastatic model of EMP as compared to their non-metastatic counterparts. Using this approach, we demonstrate that upregula ...[more]