Ontology highlight
ABSTRACT:
SUBMITTER: Xing Y
PROVIDER: S-EPMC7019016 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Xing Yongqiang Y Yang Wuritu W Liu Guoqing G Cui Xiangjun X Meng Hu H Zhao Hongyu H Zhao Xiujuan X Li Jun J Liu Zhe Z Zhang Michael Q MQ Cai Lu L
Frontiers in bioengineering and biotechnology 20200207
The mechanism of alternative pre-mRNA splicing (AS) during preimplantation development is largely unknown. In order to capture the dynamic changes of AS occurring during embryogenesis, we carried out bioinformatics analysis based on scRNA-seq data over the time-course preimplantation development in mouse. We detected numerous previously-unreported differentially expressed genes at specific developmental stages and investigated the nature of AS at both minor and major zygotic genome activation (Z ...[more]