Ontology highlight
ABSTRACT:
SUBMITTER: Stevens VM
PROVIDER: S-EPMC7019392 | biostudies-literature | 2019 Jan-Dec
REPOSITORIES: biostudies-literature
Stevens Victoria M VM Trujillo Toby T Mueller Scott W SW MacLaren Robert R Reynolds Paul M PM Kiser Tyree H TH
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20190101
Andexanet alfa is approved for the reversal of factor Xa inhibitors in patients with major bleeding events. We aimed to review the incidence of effective hemostasis with andexanet alfa in a real-world environment. This retrospective cohort included patients hospitalized for a major bleed that resulted in andexanet alfa administration. The primary outcome was effective hemostasis at 12 hours after andexanet alfa treatment. Thromboembolic events and mortality within 30 days were also assessed. Ove ...[more]