Ontology highlight
ABSTRACT:
SUBMITTER: Lee JK
PROVIDER: S-EPMC7020004 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Lee Jae Kyung JK Oh Soo-Jin SJ Park Hosun H Shin Ok Sarah OS
Viruses 20191218 1
The placenta is a unique mixed organ, composed of both maternal and fetal tissues, that is formed only during pregnancy and serves as the key physiological and immunological barrier preventing maternal-fetal transmission of pathogens. Several viruses can circumvent this physical barrier and enter the fetal compartment, resulting in miscarriage, preterm birth, and birth defects, including microcephaly. The mechanisms underlying viral strategies to evade the protective role of placenta are poorly ...[more]