Ontology highlight
ABSTRACT:
SUBMITTER: Vanherle L
PROVIDER: S-EPMC7020256 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Vanherle Lotte L Matuskova Hana H Don-Doncow Nicholas N Uhl Franziska E FE Meissner Anja A
Frontiers in cell and developmental biology 20200207
Mounting evidence indicates that the presence of cardiovascular disease (CVD) and risk factors elevates the incidence of cognitive impairment (CI) and dementia. CVD and associated decline in cardiovascular function can impair cerebral blood flow (CBF) regulation, leading to the disruption of oxygen and nutrient supply in the brain where limited intracellular energy storage capacity critically depends on CBF to sustain proper neuronal functioning. During hypertension and acute as well as chronic ...[more]