Association of HSPA1B Polymorphisms with Paranoid Schizophrenia in a Polish Population.
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ABSTRACT:
SUBMITTER: Kowalczyk M
PROVIDER: S-EPMC7021735 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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Association of HSPA1B Polymorphisms with Paranoid Schizophrenia in a Polish Population.
Kowalczyk Malgorzata M Kucia Krzysztof K Owczarek Aleksander A Suchanek-Raif Renata R Merk Wojciech W Fila-Danilow Anna A Paul-Samojedny Monika M Choreza Piotr P Kowalski Jan J
Neuromolecular medicine 20191023 1
This study aimed to find the potential association between HSPA1B polymorphisms and risk of paranoid schizophrenia, clinical variables of the disease, and suicidal behavior. A total of 901 unrelated Polish subjects of Caucasian origin (377 schizophrenia patients and 524 controls) were recruited. Four single-nucleotide polymorphisms (SNP) were genotyped using PCR-RFLP (rs539689, rs9281590) and TaqMan assays (rs263979, rs6547452). A strong tendency towards statistical significance (p = 0.051) was ...[more]
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