Ontology highlight
ABSTRACT:
SUBMITTER: Waldchen F
PROVIDER: S-EPMC7021797 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Wäldchen Felix F Schlegel Jan J Götz Ralph R Luciano Michael M Schnermann Martin M Doose Sören S Sauer Markus M
Nature communications 20200214 1
The molecular organization of receptors in the plasma membrane of cells is paramount for their functionality. We combined lattice light-sheet (LLS) microscopy with three-dimensional (3D) single-molecule localization microscopy (dSTORM) and single-particle tracking to quantify the expression and distribution, and mobility of CD56 receptors on whole fixed and living cells, finding that CD56 accumulated at cell-cell interfaces. For comparison, we investigated two other receptors, CD2 and CD45, whic ...[more]