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Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles.

ABSTRACT: This study attempts to obtain and test the bioactivities of leaf extracts from a medicinal plant, Geranium wallichianum (GW), when conjugated with zinc oxide nanoparticles (ZnONPs). The integrity of leaf extract-conjugated ZnONPs (GW-ZnONPs) was confirmed using various techniques, including Ultraviolet-visible spectroscopy, X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, energy-dispersive spectra (EDS), scanning electron microscopy, transmission electron microscopy, and Raman spectroscopy. The size of ZnONPs was approximately 18 nm, which was determined by TEM analysis. Additionally, the energy-dispersive spectra (EDS) revealed that NPs have zinc in its pure form. Bioactivities of GW-ZnONPs including antimicrobial potentials, cytotoxicity, antioxidative capacities, inhibition potentials against ?-amylase, and protein kinases, as well as biocompatibility were intensively tested and confirmed. Altogether, the results revealed that GW-ZnONPs are non-toxic, biocompatible, and have considerable potential in biological applications.

SUBMITTER: Abbasi BA

PROVIDER: S-EPMC7022592 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Bioactivities of <i>Geranium wallichianum</i> Leaf Extracts Conjugated with Zinc Oxide Nanoparticles.

Abbasi Banzeer Ahsan BA Iqbal Javed J Ahmad Riaz R Zia Layiq L Kanwal Sobia S Mahmood Tariq T Wang Canran C Chen Jen-Tsung JT

Biomolecules 20191226 1

This study attempts to obtain and test the bioactivities of leaf extracts from a medicinal plant, <i>Geranium wallichianum</i> (GW), when conjugated with zinc oxide nanoparticles (ZnONPs). The integrity of leaf extract-conjugated ZnONPs (GW-ZnONPs) was confirmed using various techniques, including Ultraviolet-visible spectroscopy, X-Ray Diffraction, Fourier Transform Infrared Spectroscopy, energy-dispersive spectra (EDS), scanning electron microscopy, transmission electron microscopy, and Raman ...[more]

PMID: 31888037

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Dataset Information

Bioactivities of Geranium wallichianum Leaf Extracts Conjugated with Zinc Oxide Nanoparticles.

Publications

Bioactivities of <i>Geranium wallichianum</i> Leaf Extracts Conjugated with Zinc Oxide Nanoparticles.

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