Ontology highlight
ABSTRACT:
SUBMITTER: Sahito B
PROVIDER: S-EPMC7024240 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Sahito Benazir B Zhang Qian Q Yang Haifeng H Peng Lin L Gao Xiuge X Kashif Jam J Ul Aabdin Zain Z Jiang Shanxiang S Wang Liping L Guo Dawei D
Molecules (Basel, Switzerland) 20200113 2
This study aimed to develop nanostructured lipid carriers (NLCs) for improved oral absorption of tilmicosin (TMS) in broilers. Thus, palmitic acid, lauric acid, and stearic acid were selected as solid lipids to formulate TMS-pNLCs, TMS-lNLCs, and TMS-sNLCs, respectively. They showed similar physicochemical properties and meanwhile possessed excellent storage and gastrointestinal stability. The TMS interacted with the lipid matrix and was encapsulated efficiently in NLCs in an amorphous structure ...[more]