Inverse probability weighted distributed lag effects of short-term exposure to PM_2.5 and ozone on CVD hospitalizations in New England Medicare participants - Exploring the causal effects.

ABSTRACT:

Background

Although many studies have established significant associations between short-term air pollution and the risk of getting cardiovascular diseases, there is a lack of evidence based on causal distributed lag modeling.

Methods

Inverse probability weighting (ipw) propensity score models along with conditional logistic outcome regression models based on a case-crossover study design were applied to get the causal unconstrained distributed (lag0-lag5) as well as cumulative lag effect of short-term exposure to PM_2.5/Ozone on hospital admissions of acute myocardial infarction (AMI), congestive heart failure (CHF) and ischemic stroke (IS) among New England Medicare participants during 2000-2012. Effect modification by gender, race, secondary diagnosis of Chronic

SUBMITTER: Qiu X 

PROVIDER: S-EPMC7024653 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature