Clinical, microbiological, and immunological evaluation of patients in corrective orthodontic treatment.

ABSTRACT: BACKGROUND:The objective was to analyze clinical, microbiological, and immunological periodontal parameters in patients in corrective orthodontic treatment. MATERIALS AND METHODS:Twenty-eight patients were selected. Plaque index (PI), bleeding on probing (BOP), width of keratinized gingiva, levels of 40 bacterial species, and of 3 cytokines (IL-1?, MMP-8, and TNF-?) in gingival crevicular fluid (GCF) were evaluated at T0, before orthodontic treatment; T1, 6?months; and T2, 12?months post-treatment. Non-parametric, Friedman, Wilcoxon, ANOVA, and Spearman correlation coefficient tests were used for statistical analyses, with the significance level of 5%. RESULTS:No significant difference was found for the width of keratinized gingiva, but PI presented a significant increase at T1 and T2 (p??0.05). In the microbiological analysis, red complex pathogens were in significantly greater proportions in T2 compared with T0 (p?

SUBMITTER: Shirozaki MU 

PROVIDER: S-EPMC7024686 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature