Ontology highlight
ABSTRACT:
SUBMITTER: Schiffer C
PROVIDER: S-EPMC7024840 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Schiffer Christian C Rieger Steffen S Brenker Christoph C Young Samuel S Hamzeh Hussein H Wachten Dagmar D Tüttelmann Frank F Röpke Albrecht A Kaupp U Benjamin UB Wang Tao T Wagner Alice A Krallmann Claudia C Kliesch Sabine S Fallnich Carsten C Strünker Timo T
The EMBO journal 20200119 4
Navigation of sperm in fluid flow, called rheotaxis, provides long-range guidance in the mammalian oviduct. The rotation of sperm around their longitudinal axis (rolling) promotes rheotaxis. Whether sperm rolling and rheotaxis require calcium (Ca<sup>2+</sup> ) influx via the sperm-specific Ca<sup>2+</sup> channel CatSper, or rather represent passive biomechanical and hydrodynamic processes, has remained controversial. Here, we study the swimming behavior of sperm from healthy donors and from in ...[more]