Ontology highlight
ABSTRACT:
SUBMITTER: Na HG
PROVIDER: S-EPMC7025384 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Na Hyo Gyeong HG Imran Ali A Kim Kyuneun K Han Hong Sik HS Lee Young Jin YJ Kim Myung-Jin MJ Yun Chang-Soo CS Jung Young-Sik YS Lee Joo-Youn JY Han Soo Bong SB
ACS medicinal chemistry letters 20200109 2
Hepatitis B virus (HBV) remains a major health concern with 260 million people having been infected globally, and approximately 680,000 deaths have occurred annually from cirrhosis and liver cancer. The modulation of HBV capsid assembly has emerged as a promising therapeutic approach for curing chronic HBV infection. Small-molecule capsid assembly modulators (CAMs) can broadly be classified as heteroaryldihydropyrimidines and sulfamoylbenzamides (SBAs). SBAs are capsid activators that inhibit vi ...[more]