Genetics of Bipolar Disorder: Recent Update and Future Directions.
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ABSTRACT:
SUBMITTER: Goes FS
PROVIDER: S-EPMC7025814 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Publications
Genetics of Bipolar Disorder: Recent Update and Future Directions.
The Psychiatric clinics of North America 20160301 1
Although genetic studies of Bipolar Disorder have been pursued for decades, it has only been in the last several years that clearly replicated findings have emerged. These findings, typically of modest effects, point to a polygenic genetic architecture consisting of multiple common and rare susceptibility variants. While larger genome-wide association studies are ongoing, the advent of whole exome and genome sequencing should lead to the identification of rare, and potentially more penetrant, va ...[more]
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