Ontology highlight
ABSTRACT:
SUBMITTER: Sankaranarayanan SR
PROVIDER: S-EPMC7025860 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Sankaranarayanan Sundar Ram SR Ianiri Giuseppe G Coelho Marco A MA Reza Md Hashim MH Thimmappa Bhagya C BC Ganguly Promit P Vadnala Rakesh Netha RN Sun Sheng S Siddharthan Rahul R Tellgren-Roth Christian C Dawson Thomas L TL Heitman Joseph J Sanyal Kaustuv K
eLife 20200120
Genomic rearrangements associated with speciation often result in variation in chromosome number among closely related species. <i>Malassezia</i> species show variable karyotypes ranging between six and nine chromosomes. Here, we experimentally identified all eight centromeres in <i>M. sympodialis</i> as 3-5-kb long kinetochore-bound regions that span an AT-rich core and are depleted of the canonical histone H3. Centromeres of similar sequence features were identified as CENP-A-rich regions in < ...[more]