Unknown

Dataset Information

0

A broad autism phenotype expressed in facial morphology.


ABSTRACT: Autism spectrum disorder is a heritable neurodevelopmental condition diagnosed based on social and communication differences. There is strong evidence that cognitive and behavioural changes associated with clinical autism aggregate with biological relatives but in milder form, commonly referred to as the 'broad autism phenotype'. The present study builds on our previous findings of increased facial masculinity in autistic children (Sci. Rep., 7:9348, 2017) by examining whether facial masculinity represents as a broad autism phenotype in 55 non-autistic siblings (25 girls) of autistic children. Using 3D facial photogrammetry and age-matched control groups of children without a family history of ASD, we found that facial features of male siblings were more masculine than those of male controls (n?=?69; p?

SUBMITTER: Tan DW 

PROVIDER: S-EPMC7026150 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

A broad autism phenotype expressed in facial morphology.

Tan Diana Weiting DW   Maybery Murray T MT   Gilani Syed Zulqarnain SZ   Alvares Gail A GA   Mian Ajmal A   Suter David D   Whitehouse Andrew J O AJO  

Translational psychiatry 20200116 1


Autism spectrum disorder is a heritable neurodevelopmental condition diagnosed based on social and communication differences. There is strong evidence that cognitive and behavioural changes associated with clinical autism aggregate with biological relatives but in milder form, commonly referred to as the 'broad autism phenotype'. The present study builds on our previous findings of increased facial masculinity in autistic children (Sci. Rep., 7:9348, 2017) by examining whether facial masculinity  ...[more]

Similar Datasets

| S-EPMC6249104 | biostudies-literature
| S-EPMC8765621 | biostudies-literature
| S-EPMC5996536 | biostudies-literature
| S-EPMC5570931 | biostudies-literature
| S-EPMC7901138 | biostudies-literature
| S-EPMC7217184 | biostudies-literature
| S-EPMC3327801 | biostudies-literature
| S-EPMC1285182 | biostudies-literature
| S-EPMC4813327 | biostudies-literature
| S-EPMC6206510 | biostudies-literature