Ontology highlight
ABSTRACT:
SUBMITTER: Hong T
PROVIDER: S-EPMC7026389 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Hong Tongtong T Jiang Yanxialei Y Yue Zihong Z Song Xinyue X Wang Zonghua Z Zhang Shusheng S
Frontiers in chemistry 20200211
Upconversion nanoparticles (UCNPs)-based photodynamic nanotheranostic agents could address the main drawbacks of photosensitizer molecules (PSs) including instability in aqueous solution and rapid clearance. Due to the relatively weak luminescence intensity of UCNPs and insufficient reactive oxygen species (ROSs), UCNPs-based photodynamic therapy (UCNPs-PDT) was discounted for deep-seated tumors. Thus, we proposed a PSs-modulated sensitizing switch strategy. Indocyanine green (ICG) as an NIR org ...[more]