Assessment of fasted and fed gastrointestinal contraction frequencies in healthy subjects using continuously tagged MRI.

ABSTRACT:

Background

Continuously tagged MRI during free breathing can assess bowel motility at frequencies as low as the slow wave, motility pattern range. This study aimed to evaluate noninvasive gastrointestinal-tagged MRI for small bowel motility assessment and to observe the physiological response to a 300-kcal meal challenge in healthy, overnight-fasted volunteers.

Methods

After overnight fasting, 16 healthy subjects (7 women, mean age 25.5, range 19-37 years) underwent a free breathing, tagged MRI scan to capture small bowel motility. Each subject underwent a (a) baseline motility scan, (b) food challenge, (c) postchallenge scan, and (d) second postchallenge scan (after 20 minutes). Motility was quantified using a frequency analysis technique for measuring the spectral power of

SUBMITTER: de Jonge CS 

PROVIDER: S-EPMC7027525 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature