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Physical activity, sitting, and risk factors of cardiovascular disease: a cross-sectional analysis of the CARRS study.


ABSTRACT: We aimed to estimate the associations between substituting 30-min/day of walking or moderate-to-vigorous physical activity (MVPA) for 30 min/day of sitting and cardiovascular risk factors in a South Asian population free of cardiovascular disease. We collected information regarding sitting and physical activity from a representative sample of 6991 participants aged 20 years and above from New Delhi, India and Karachi, Pakistan enrolled in 2010-2011 in the Center for cArdio-metabolic Risk Reduction in South Asia study using the International Physical Activity Questionnaire (short form). We conducted isotemporal substitution analyses using multivariable linear regression models to examine the cross-sectional associations between substituting MVPA and walking for sitting with cardiovascular risk factors. Substituting 30 min/day of MVPA for 30 min/day of sitting was associated with 0.08 mmHg lower diastolic blood pressure (??=?-0.08 [-?0.15, -?0.0003]) and 0.13 mg/dl higher high-density lipoprotein cholesterol (??=?0.13 [0.04, 0.22]). Substituting 30 min/day of walking for 30 min/day of sitting was associated with 0.08 kg/m2 lower body mass index (??=?-0.08 [-?0.15, -?0.02]), and 0.25 cm lower waist circumference (??=?-0.25 [-?0.39, -?0.11]). In conclusion, substituting time engaged in more-active pursuits for time engaged in less-active pursuits was associated with modest but favorable cardiovascular risk factor improvements among South Asians.

SUBMITTER: Wei J 

PROVIDER: S-EPMC7027929 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Physical activity, sitting, and risk factors of cardiovascular disease: a cross-sectional analysis of the CARRS study.

Wei Jingkai J   Anjana Ranjit Mohan RM   Goenka Shifalika S   Lobelo Felipe F   Shivashankar Roopa R   Kadir Muhammad Masood MM   Tandon Nikhil N   Mohan Viswanathan V   Narayan K M Venkat KMV   Prabhakaran Dorairaj D   Ali Mohammed K MK  

Journal of behavioral medicine 20181116 3


We aimed to estimate the associations between substituting 30-min/day of walking or moderate-to-vigorous physical activity (MVPA) for 30 min/day of sitting and cardiovascular risk factors in a South Asian population free of cardiovascular disease. We collected information regarding sitting and physical activity from a representative sample of 6991 participants aged 20 years and above from New Delhi, India and Karachi, Pakistan enrolled in 2010-2011 in the Center for cArdio-metabolic Risk Reducti  ...[more]

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