Ontology highlight
ABSTRACT:
SUBMITTER: Sa JK
PROVIDER: S-EPMC7029441 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Sa Jason K JK Hong Jung Yong JY Lee In-Kyoung IK Kim Ju-Sun JS Sim Moon-Hee MH Kim Ha Jung HJ An Ji Yeong JY Sohn Tae Sung TS Lee Joon Ho JH Bae Jae Moon JM Kim Sung S Kim Kyoung-Mee KM Kim Seung Tae ST Park Se Hoon SH Park Joon Oh JO Lim Ho Yeong HY Kang Won Ki WK Her Nam-Gu NG Lee Yeri Y Cho Hee Jin HJ Shin Yong Jae YJ Kim Misuk M Koo Harim H Kim Mirinae M Seo Yun Jee YJ Kim Ja Yeon JY Choi Min-Gew MG Nam Do-Hyun DH Lee Jeeyun J
Genome medicine 20200218 1
<h4>Background</h4>Gastric cancer is among the most lethal human malignancies. Previous studies have identified molecular aberrations that constitute dynamic biological networks and genomic complexities of gastric tumors. However, the clinical translation of molecular-guided targeted therapy is hampered by challenges. Notably, solid tumors often harbor multiple genetic alterations, complicating the development of effective treatments.<h4>Methods</h4>To address such challenges, we established a c ...[more]