The effect of modifiable risk factors on breast cancer aggressiveness among black and white women.

ABSTRACT:

Introduction

Although breast cancer incidence is higher among white women, black women are more likely to have aggressive tumors with less favorable histology, and to have a worse prognosis. Obesity and alcohol consumption have been identified as two modifiable risk factors for breast cancer, while physical activity may offer protection. Little however is known about the association of these factors with race on the severity of breast cancer.

Methods

Data collected as part of a large prospective study looking at insulin resistance and race among women with breast cancer was queried for patient characteristics, lifestyle factors and tumor characteristics. The association with Nottingham Prognostic Index (NPI) was assessed with different models using univariate and multivariat

SUBMITTER: Killelea BK 

PROVIDER: S-EPMC7029579 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature